Research interest: Potential anti-Alzheimer and anticancer drugs. Application of MOFs and metal nanoparticles in drug delivery systems and for biosensing. MOF as new materials for effective detection and removal of xenobiotics from the environment.
Education:
PhD in Biophysical Chemistry (2017), University of Belgrade, Faculty of Physical Chemistry, PhD thesis title: “The interaction of bipyridyl gold(III)complexes and polyoxotungstates with Na+/K+-ATPaze and acetylcholinesterase”.
MSc in Chemistry (2011), University of Belgrade, Faculty of Chemistry, MSc thesis title: “Oxidation of quercetin by tetrachloraurate(III) ion in acidic media”.
BSc in Chemistry (2006), University of Belgrade, Faculty of Chemistry, BSc thesis title: “Kinetic of reaction between [AuCl4 ]– and quercetin”.
Career:
2006 – 2008., Department of Physical Chemistry, Institute of Nuclear Sciences Vinča
2011 – present, Department of Physical Chemistry, Institute of Nuclear Sciences Vinča
04/2023 – 10/2023 – postdoctoral fellowship – Department of Chemistry, KU Leuven, Belgium
Active projects:
Program topic: Design and development of complex chemical structures and innovative methods in the treatment of neurodegenerative disorders, cancer and in the removal of xenobiotics from the environment (2024-present); project leader.
Bilateral project with Turkey: Cooperation between the Department of Natural and Mathematical Sciences, Ozyegin University, Istanbul, and the Institute of Nuclear Sciences VINCA, Belgrade, Serbia. Project title: “MOF compounds as carriers for tetrahydroisoquinoline based inhibitors of acetylcholinesterase – improved solution for the treatment of Alzheimer’s disease” (2024-2026); project leader.
Project: “Plasmonic-based light harvesting for photocatalytic microfluidic devices” (2023-2026), PlasmaHarvest – Program PRIZMA, Science Fund of the Republic of Serbia; participant.
Cost action CA22147 – European metal-organic framework network: combining research and development to promote technological solutions (EU4MOFs) (2023-2027); Member of Management Committee for Serbia
List of five selected publications:
- Jovanović, D., Filipović, A., Janić, G., Lazarević Pašti, T., Bondžić, B.P., Bondžić, A.M*. “Targeting Alzheimer’s Disease: Evaluating the Efficacy of C-1 Functionalized N-Aryl-Tetrahydroisoquinolines as Cholinergic Enzyme Inhibitors and Promising Therapeutic Candidates” Int. J. Mol. Sci. 2024, 25, 1033. https://doi.org/10.3390/ijms25021033
- Bondžić А.М.*, Jovanović D., Arsenijević N., Laban B., Lazarević Pašti T., Klekotka U., Bondžić B.P., ““Soft Protein Corona” as the Stabilizer of the Methionine-Coated Silver Nanoparticles in the Physiological Environment: Insights into the Mechanism of the Interaction”, International Journal of Molecular Sciences, 2022, 23(16), 8985. https://doi.org/10.3390/ijms23168985
- Bondžić A. M.*, Lazarević Pašti T. D., Pašti I. A., Bondžić B. P., Momčilović M., Loosen A., Parac-Vogt T. N. “Synergistic Effect of Sorption and Hydrolysis by NU-1000 Nanostructures for Removal and Detoxification of Chlorpyrifos”, ACS Applied Nano Materials, 2022, 5, 3, 3312–3324. https://doi.org/10.1021/acsanm.1c03863
- Bondžić A. M.,* Žakula J. J., Korićanac L. B., Keta O. D., Janjić G. V., Đorđević I. S. Rajković S. U. “Cytotoxic activity and influence on acetylcholinesterase of series dinuclear platinum(II) complexes with aromatic nitrogen-containing heterocyclic bridging ligands: Insights in the mechanisms of action”, Chemico-Biological Interactions, 2022, 351, 109708. https://doi.org/10.1016/j.cbi.2021.109708
- Bondžić, A. M.*, Senćanski, M. V., Vujačić Nikezić, A.V., Kirillova, M. V., André, V., Kirillov, A. M.*, Bondžić, B. P. “Aminoalcoholate-driven tetracopper(II) cores as dual acetyl and butyrylcholinesterase inhibitors: experimental and theoretical elucidation of the mechanism of action” Journal of Inorganic Biochemistry, 2020, 205, 110990. https://doi.org/10.1016/j.jinorgbio.2019.110990